Enhanced thermal stability for adenoviral vectors through spray drying
US10752876B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Sep 2, 2016 |
| Grant date | Aug 25, 2020 |
| Priority date | — |
| Expiry date | Jan 20, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/10351
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present application includes stabilized adenovirus compositions comprising an adenovirus and an excipient, wherein the excipient comprises a mixture of dextran and mannitol in amounts effective to maintain at least 40% of the adenovirus activity after spray drying.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.