Stabilized liquid and lyophilized ADAMTS13 formulations
US10758599B2 · kind B2 · utility
10Cited by
11References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 14, 2019 |
| Grant date | Sep 1, 2020 |
| Priority date | — |
| Expiry date | Feb 14, 2039 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to formulations of ADAMTS13 with enhanced or desirable properties. As such, the invention provides liquid and lyophilized formulations of ADAMTS13 that are suitable for pharmaceutical administration. Among other aspects, the present invention also provides methods of treating various diseases and conditions related to VWF and/or ADAMTS13 dysfunction in a subject. Also provided herein are kits comprising ADAMTS13 formulations useful for the treatment of various diseases and conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.