Medical macromolecular microsphere adsorbent for a blood perfusion apparatus and a preparation method thereof
US10758889B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Jun 7, 2018 |
| Grant date | Sep 1, 2020 |
| Priority date | — |
| Expiry date | Apr 30, 2039 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J20/3071
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A medical macromolecular microsphere adsorbent for a blood perfusion apparatus and a preparation method thereof are provided. The polystyrene-divinylbenzene microspheres are graded by different pore sizes and specific surface areas, medically purified, and grafted by a bioactivity-controlled grafting technology. In the microsphere adsorbent, the volume ratio of microspheres with pore sizes of 1-10 μm, 10-100 μm and 100 μm is 1:(1-10):(1-20), the content of residual monomers in the microsphere has O.D190-400 nm≤0.03. The microsphere adsorbent not only can adsorb harmful micromolecules in blood but also can effectively adsorb harmful medium-molecules and macromolecules in blood, thereby meeting clinical application demands.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.