Prodrugs of kallikrein inhibitors
US10759759B2 · kind B2 · utility
1Cited by
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30Claims
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Assignee
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Key dates
| Filing date | Oct 27, 2017 |
| Grant date | Sep 1, 2020 |
| Priority date | — |
| Expiry date | Oct 27, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are compounds of formula I, II, and III, and pharmaceutically acceptable salts thereof, which are inhibitors of kallikrein. Also provided are pharmaceutical compositions comprising such a compound, and methods involving use of the compounds and compositions in the treatment and prevention of acquired or hereditary angioedema, or other diseases and conditions characterized by aberrant kallikrein activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.