Heterocyclic carboxylic acid amide ligand and applications thereof in copper catalyzed coupling reaction of aryl halogeno substitute

US10759765B2 · kind B2 · utility

Assignee

• CE Pharm Co., Ltd. · CN

Inventors

• Dawei Ma · Shanghai, CN
• Wei Zhou · Scotch Plains, US
• Mengyang Fan · Shanghai, CN
• Haibo Wu · Shanghai, CN
• Junli Yin · Shanghai, CN
• Xi Jiang · Virginia Beach, US
• Yuntong Zhai · Shanghai, CN
• Songtao Niu · Shanghai, CN

Key dates

• Filing date: Apr 14, 2017
• Grant date: Sep 1, 2020
• Expiry date: Apr 14, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C209/60
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Provided are a heterocyclic carboxylic acid amide ligand and applications thereof in a copper catalyzed coupling reaction. Specifically, provided are uses of a compound represented by formula (I), definitions of radical groups being described in the specifications. The compound represented by formula (I) can be used as the ligand in the copper catalyzed coupling reaction of the aryl halogeno substitute, and is used or catalyzing the coupling reaction for forming the aryl halogeno substitute having C—N, C—O, C—S and other bonds.