Patent · US Active

Methylphenidate-prodrugs, processes of making and using the same

US10759778B2 · kind B2 · utility

3Cited by

6References

23Claims

0Family size

Assignee

KEMPHARM, INC. · US

Inventors

Travis Mickle · Four Corners, US
Sven Guenther · Coralville, US
Guochen Chi · Coralville, US

Key dates

Filing date	Jun 4, 2019
Grant date	Sep 1, 2020
Priority date	—
Expiry date	Jun 4, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D211/34
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present technology is directed to compositions comprising d-threo-methylphenidate conjugates and unconjugated methylphenidate. The present technology also relates to compositions and oral formulations comprising d-threo-methylphenidate conjugated to nicotinoyl-L-serine, and/or a pharmaceutically acceptable salt thereof, and unconjugated methylphenidate and/or a pharmaceutically acceptable salt thereof. The present technology additionally relates to a pharmaceutical kit containing the composition comprising d-threo-methylphenidate conjugated to nicotinoyl-L-serine, and/or a pharmaceutically acceptable salt thereof, and unconjugated methylphenidate and/or a pharmaceutically acceptable salt thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.