Benzofuran derivative, preparation method thereof and use thereof in medicine
US10759787B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Nov 2, 2016 |
| Grant date | Sep 1, 2020 |
| Priority date | — |
| Expiry date | Nov 2, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a benzofuran derivative, a preparation method thereof and a use thereof in medicine. In particular, the present invention relates to the benzofuran derivative as shown by general formula (I), the preparation method thereof, a pharmaceutical composition containing the derivative, and uses thereof as an EZH2 inhibitor and in the prevention and/or treatment of diseases such as tumours and cancers, etc., and in particular, uses thereof in the prevention and/or treatment of non-Hodgkin's lymphoma, diffuse large B-cell lymphoma, follicular lymphoma and synovial sarcoma, wherein the definitions of the substituents in the general formula (I) are the same as those defined in the description.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.