ABT-199 addition salt and crystal form thereof, preparation method thereof, and pharmaceutical composition thereof
US10759798B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Sep 14, 2016 |
| Grant date | Sep 1, 2020 |
| Priority date | — |
| Expiry date | Sep 14, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/13
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Crystalline forms, preparation methods and pharmaceutical compositions of ABT-199 monohydrochloride and ABT-199 dihydrochloride are disclosed. Compared with known ABT-199, they have one or more improved properties. They can be used to prepare drugs for the treatment and/or prevention of one or more diseases associated with overexpression of an anti-apoptotic BCL-2 family protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.