Antibody variants and uses thereof
US10759867B2 · kind B2 · utility
9Cited by
2References
6Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 6, 2012 |
| Grant date | Sep 1, 2020 |
| Priority date | — |
| Expiry date | Mar 5, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are polypeptides and related antibodies comprising a variant Fc domain. The variant Fc domain provide for stabilized Fc:Fc interactions when the polypeptide(s), antibody or antibodies are bound to its target, antigen or antigens on the surface of a cell, thus providing for improved effector functions, such as CDC-response.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.