Mechanical transfection devices and methods
US10760040B1 · kind B1 · utility
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15Claims
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Key dates
| Filing date | Jun 29, 2015 |
| Grant date | Sep 1, 2020 |
| Priority date | — |
| Expiry date | Jun 9, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12M47/04
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A transfection device suitable for delivery of various macrostructures (e.g., mitochondria, bacteria, liposomes) is described and uses mechanical force to thereby induce active endocytosis in a target cell. Contemplated devices are able to achieve high throughput of transfected cells that remain viable and are capable of producing colonies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.