Patent · US Active

Aryl-2,2′-tandem bisthiazole compound and preparation method and use thereof

US10766889B2 · kind B2 · utility

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1References

19Claims

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Assignee

SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES · CN

Inventors

Fajun Nan · Shanghai, CN
Jia-He Li · Cockeysville, US
Jian Ding · Shanghai, CN
Meiyu Geng · Shanghai, CN
Yangming Zhang · Shanghai, CN
Yi Chen · Shanghai, CN
Yubo Zhou · Shanghai, CN
Chaojun GONG · Suzhou, CN
Mingbo Su · Shanghai, CN
Anhui Gao · Shanghai, CN

Key dates

Filing date	Aug 24, 2017
Grant date	Sep 8, 2020
Priority date	—
Expiry date	Aug 24, 2037

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/55
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention describes an aryl-2,2′-tandem bisthiazole compound and a preparation method and the use thereof. In particular, disclosed in the present invention are an aryl-2,2′-tandem bisthiazole compound with the structure as shown in general formula I and the preparation method thereof and use thereof as a histone deacetylase inhibitor in the preparation of antitumor drugs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.