Imidazo[4,5-c] ring compounds containing guanidine substituted benzamide groups
US10766896B2 · kind B2 · utility
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24Claims
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Key dates
| Filing date | Feb 27, 2018 |
| Grant date | Sep 8, 2020 |
| Priority date | — |
| Expiry date | Feb 27, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Imidazo[4,5-c] ring compounds of formula I, (particularly imidazo4,5-c]quinolines, 6,7,8,9-tetrahydroimidazo[4,5-c]quinolines, imidazo[4,5-c]naphthyridines, and 6,7,8,9-tetrahydroimidazo[4,5-c]naphthyridine compounds) having a guanidine substituted benzamide that is attached at the N−1 position by a linking group, pharmaceutical compositions containing the compounds, and methods of making the compounds are disclosed. Methods of use of the compounds as immune response modifiers, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.