Proteases with improved enzyme stability in detergents

US10767142B2 · kind B2 · utility

Assignee

• Henkel AG & Co. KGaA · DE

Inventors

• Nina Mussmann · Willich, DE
• Timothy O'Connell · Fürstenfeldbruck, DE
• Daniela Herbst · Goldkronach, DE
• Inken Prueser · Dressendorf, DE
• Christian Degering · Erkrath, DE
• Sabine Griemert · Monheim am Rhein, DE
• Thorsten Eggert · Hattingen, DE
• Christian Leggewie · Mülheim an der Ruhr, DE

Key dates

• Filing date: Mar 7, 2017
• Grant date: Sep 8, 2020
• Expiry date: Jun 25, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y304/21062
• WIPO field: Basic materials chemistry
• WIPO sector: Chemistry

Abstract

The present disclosure relates to proteases having an amino acid sequence with at least about 70% sequence identity to the amino acid sequence given in SEQ ID NO:2, over the entire length thereof, and comprising an amino acid substitution at at least one of the positions P9, Q62, D101, N130, G166, N187, 5216, N238 or Q271, based in each case on the numbering according to SEQ ID NO:2. The present disclosure also relates to the production and use thereof. Such proteases exhibit very good stability, in particular storage stability, while at the same time having a good cleaning performance.