Patent · US Active

Method for analyzing an NMR spectrum of a lipoprotein-containing sample

US10768251B2 · kind B2 · utility

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12Claims
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Key dates

Filing dateDec 12, 2017
Grant dateSep 8, 2020
Priority date
Expiry dateDec 12, 2037

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01R33/4625
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Disclosed is a method for analyzing an NMR spectrum of a lipoprotein-containing sample. The method includes the following steps: a) defining a spectral range to be analyzed of at least 0.5 ppm of an NMR spectrum of a lipoprotein-containing sample; b) fitting a first spectral function of a first individual lipid component and at least one further spectral function of a further individual lipid component into the whole spectral range to be analyzed; and c) determining a concentration or an amount of the first individual lipid component and the further individual lipid component and therefrom a concentration or an amount of the first defined lipoprotein class or lipoprotein subclass in the lipoprotein-containing sample and optionally of each other defined lipoprotein class or lipoprotein subclass based on the fitting operations of step b).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.