Patent · US Active

Indolo substituted piperidine compound as estrogen receptor down-regulator

US10774081B2 · kind B2 · utility

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5Claims

0Family size

Assignees

Inventors

Jianyu LU · Shanghai, CN
Charles Z. Ding · San Mateo, US
Xu ZENG · Shanghai, CN
Huijun HE · Shanghai, CN
Shuhui CHEN · Shanghai, CN
Lihong Hu · Shanghai, CN
Jiaqiang Dong · 浮桥镇, CN
Tie-Lin Wang · Shanghai, CN

Key dates

Filing date	Oct 30, 2017
Grant date	Sep 15, 2020
Priority date	—
Expiry date	Oct 30, 2037

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed in the present invention is a type of indole substituted piperidine compounds as an estrogen receptor down-regulator. Specifically disclosed are a compound as shown in formula (I), a pharmaceutically acceptable salt, hydrate or prodrug thereof, a preparation method therefor, a pharmaceutical composition thereof, and a use thereof as an estrogen receptor down-regulator in the treatment of estrogen receptor positive breast cancers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.