Patent · US Active

Complex-specific antibodies and antibody fragments and its use

US10774154B2 · kind B2 · utility

0Cited by

2References

6Claims

0Family size

Assignee

MORPHOSYS AG · DE

Inventors

Stefan Haertle · Fürstenfeldbruck, DE
Christian Frisch · Planegg, DE
Achim Knappik · Gräfelfing, DE

Key dates

Filing date	Dec 19, 2017
Grant date	Sep 15, 2020
Priority date	—
Expiry date	Mar 14, 2038

Classification

Technology area (CPC G)Physics
CPC primaryG01N2470/06
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention provides antibodies and fragments thereof that specifically detect the complex of a specific cognate antigen-binding moiety, in particular antibodies, and its antigen. The antibodies of the present disclosure do not bind either said cognate antigen binding moiety or said antigen alone and this can be used e.g. to directly detect antigen-bound antigen-binding moieties. Further disclosed are methods for production and use of said antibodies and antibody fragments.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.