Patent · US Active

Transaminases

US10774356B2 · kind B2 · utility

0Cited by

1References

15Claims

0Family size

Assignee

C-LECTA GMBH · DE

Inventors

Andreas Vogel · Leipzig, DE
Daniel Schwarze · Jena, DE
Rico Czaja · Leipzig, DE
Sally Bayer · Leipzig, DE
Sebastian BARTSCH · Leipzig, DE

Key dates

Filing date	Jun 10, 2016
Grant date	Sep 15, 2020
Priority date	—
Expiry date	Jun 10, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y206/01
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to transaminases and their use. The ATAs according to the invention are particularly useful for catalyzing the conversion of amines to ketones and/or vice versa. Preferably, the transaminase (ATA) according to the invention comprises an amino acid sequence with at least 80% homology to SEQ ID NO:1, wherein the amino acid sequence is engineered compared to SEQ ID NO:1 such that it comprises at least a substitution selected from the group consisting of F255L, F255A, F255C, F255D, F255E, F255G, F255H, F255K, F255M, F255N, F255P, F255Q, F255R, F255S, F255T, F255V, F255W, and F255Y.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.