N-((het) arylmethyl)-heteroaryl-carboxamides compounds as plasma kallikrein inhibitors
US10781181B2 · kind B2 · utility
4Cited by
9References
36Claims
0Family size
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Key dates
| Filing date | Nov 26, 2015 |
| Grant date | Sep 22, 2020 |
| Priority date | — |
| Expiry date | Nov 26, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compounds of formula (I): (I) compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, A, B, U, D, E, W, X, Y and Z are as defined herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.