Patent · US Active

Process of preparing a peptide epoxyketone immunoproteasome inhibitor, and precursors thereof

US10781192B2 · kind B2 · utility

1Cited by

15References

20Claims

0Family size

Assignee

KEZAR LIFE SCIENCES, INC. · US

Inventors

Henry Johnson · San Bruno, US
Sean Dalziel · Burlingame, US
Dustin McMinn · Pacifica, US

Key dates

Filing date	Jun 29, 2017
Grant date	Sep 22, 2020
Priority date	—
Expiry date	Jun 29, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/13
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Disclosed herein are methods for preparing [(2S,3R)—N-[(2S)-3-(cyclopent-1-en-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-hydroxy-3-(4-methoxyphenyl)-2-[(2S)-2-[2-(morpholin-4-yl)acetamido]propanamido]propanamide (compound “G”): and precursors thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.