Transgenic microalgae and use thereof as a feed for delivery of interfering RNA molecules
US10781447B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Jul 14, 2016 |
| Grant date | Sep 22, 2020 |
| Priority date | — |
| Expiry date | Jul 14, 2036 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A40/146
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are non-propagating transgenic microalgae expressing at least one heterologous RNAi molecule. The RNAi-expressing non-propagating transgenic microalgae are used for oral delivery of the RNAi molecule to a target organism in its intact and functional form. The heterologous RNAi molecule, present within the microalgae, is characterized by being biologically active, exerting at least one specific effect on the organism consuming the microalgae or on a pathogen of said organism. In particular, the non-propagating transgenic microalgae are used as agents for biological control of animal and plant pests.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.