Double-stranded oligonucleotide molecules targeting p53 and methods of use thereof
US10781449B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Apr 2, 2018 |
| Grant date | Sep 22, 2020 |
| Priority date | — |
| Expiry date | Apr 2, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/30
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present application relates to nucleic acid compounds, compositions comprising same and methods of use thereof for treatment of various diseases, disorders and conditions. The compounds are preferably chemically synthesized and modified double-stranded nucleic acid molecules which down regulate expression of a p53 gene.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.