Method for generating proximity probes
US10781473B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 21, 2016 |
| Grant date | Sep 22, 2020 |
| Priority date | — |
| Expiry date | Oct 21, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/53
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a plurality of pairs of proximity probes, each pair being capable of binding to a different target analyte, wherein the first and second proximity probes of each pair of probes comprise universal oligonucleotides conjugated to their analyte binding moieties, and hybridised to the universal oligonucleotides are different tag oligonucleotides comprising universal complement domains common to all tag oligonucleotides and unique domains unique to each tag oligonucleotide, as well as methods for their production.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.