Methods of detecting per cell PD-L1 expression and uses thereof
US10782298B2 · kind B2 · utility
1Cited by
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20Claims
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Key dates
| Filing date | Jan 3, 2018 |
| Grant date | Sep 22, 2020 |
| Priority date | — |
| Expiry date | May 4, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods are provided for detecting the per cell programmed-death ligand 1 (PD-L1) expression of neoplasia cells. Aspects of the methods include cytometrically assaying a labeled cell suspension to quantify per cell PD-L1 expression to detect whether a neoplastic cell that expresses PD-L1 above a predetermined threshold is present in the neoplasia sample. In addition, kits that find use in practicing the subject methods are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.