Stable anti-PD-1 antibody pharmaceutical preparation and application thereof in medicine
US10786567B2 · kind B2 · utility
1Cited by
1References
18Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Sep 14, 2016 |
| Grant date | Sep 29, 2020 |
| Priority date | — |
| Expiry date | Dec 10, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A stable anti-PD-1 antibody pharmaceutical preparation and an application thereof in a medicine. The anti-PD-1 antibody pharmaceutical preparation comprises an anti-PD-1 antibody, a buffer, and can further comprise at least one type of stabilizer, and optionally can further comprise a surfactant. The anti-PD-1 antibody pharmaceutical preparation of the present invention can effectively suppress antibody aggregation and deamidation, thereby preventing degradation of an antibody product, resulting in a stable injectable pharmaceutical preparation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.