Amide derivatives of polycaffeoylquinic acids, process for producing same and uses thereof
US10786690B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 26, 2017 |
| Grant date | Sep 29, 2020 |
| Priority date | — |
| Expiry date | Apr 26, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention thus relates to amide derivatives of polysubstituted quinic acids (abbreviated to “QPS”), of general formula (IA): (IA), in which —R1A and R2A are, independently of one another: H, with the proviso that R1A and R2A are not both a hydrogen atom, a butyl group, a C7-C30 alkyl group, —a C7-C30 alkylaryl or arylalkyl group, or a C7-C18 aryl group; and —Q1, Q3, Q4 and Q5 are, independently of one another, an OH, caffeoyl, maloyl, caffeoylmaloyl ou maloylcaffeoyl group, with the proviso that at least one of these radicals is not an OH group, or to a pharmaceutically acceptable salt or stereoisomer or hydrate thereof, and also to the process for producing same, to the use thereof as a medicament, in particular for the treatment and/or prevention of inflammation and of inflammatory diseases, and to the pharmaceutical, cosmetic and nutraceutical compositions containing same.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.