Patent · US Active

Methods for purifying heterodimeric multispecific antibodies from parental homodimeric antibody species

US10787500B2 · kind B2 · utility

1Cited by

5References

22Claims

0Family size

Assignee

Adimab, LLC · US

Inventors

Juergen Hermann Nett · Lebanon, US
K. Dane Wittrup · Sharon, US
Maximiliano Vasquez · Palo Alto, US

Key dates

Filing date	Apr 8, 2016
Grant date	Sep 29, 2020
Priority date	—
Expiry date	Nov 10, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/52
WIPO fieldChemical engineering
WIPO sectorChemistry

Abstract

Methods for purifying multispecific antibodies on interest (MAIs) that co-engage at least two different antigens or epitopes (also referred to targets, used interchangeably throughout), from compositions comprising the MAI and parental homodimeric antibody species are provided, as well as reagents which may be used to practice such methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.