Nanocomplexes for delivery of saporin
US10792328B2 · kind B2 · utility
1Cited by
1References
22Claims
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Key dates
| Filing date | Jan 15, 2019 |
| Grant date | Oct 6, 2020 |
| Priority date | — |
| Expiry date | Jan 15, 2039 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/6929
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A nanocomplex, of particle size 50 nm to 1000 nm, containing saporin and a lipid-like compound, in which saporin binds to the lipid-like compound via non-covalent interaction or covalent bonding. The lipid-like compound has a hydrophilic moiety, a hydrophobic moiety, and a linker joining the hydrophilic moiety and the hydrophobic moiety. The hydrophilic moiety is optionally charged and the hydrophobic moiety has 8 to 24 carbon atoms. Also disclosed is a pharmaceutical composition containing such a nanocomplex and a pharmaceutically acceptable carrier. The nanocomplex is useful in treating diseases, such as cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.