Rapid-acting insulin composition comprising a substituted citrate
US10792335B2 · kind B2 · utility
1Cited by
14References
21Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 16, 2016 |
| Grant date | Oct 6, 2020 |
| Priority date | — |
| Expiry date | Nov 16, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition, in the form of an aqueous solution, including an insulin in hexameric form and at least one substituted citrate of formula I: in which: R1, R2, R3, identical or different, represent OH or AA, at least one of the R1, R2, R3 is an AA radical, AA is a radical resulting from a natural or synthetic aromatic amino acid comprising at least one phenyl group or indole group, substituted or not substituted, said AA radical having at least one free carboxylic acid function, and the carboxylic acid functions are in the form of a salt of an alkali metal selected from Na+ and K+.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.