Methods and compositions for treating phenylketonuria
US10792339B2 · kind B2 · utility
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20Claims
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Assignee
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Key dates
| Filing date | Jul 15, 2016 |
| Grant date | Oct 6, 2020 |
| Priority date | — |
| Expiry date | Dec 13, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y403/01024
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compositions and methods of treating hyperphenylalaninemia (e.g., phenylketonuria) in a subject in need thereof comprising administering to the subject an effective amount of a phenylalanine dehydrogenase (PheDH) polypeptide. The present invention also provides pharmaceutical formulations comprising PheDH for lowering the phenylalanine concentration in the subject (e.g., in the intestines and/or blood).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.