Conjugates comprising an GLP-1/glucagon dual agonist, a linker and hyaluronic acid
US10792367B2 · kind B2 · utility
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36Claims
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Key dates
| Filing date | Dec 1, 2017 |
| Grant date | Oct 6, 2020 |
| Priority date | — |
| Expiry date | Dec 1, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/605
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a conjugate or a pharmaceutically acceptable salt thereof comprising an GLP-1/Glucagon receptor agonist, a linker and a hyaluronic acid hydrogel bearing -L1-L2-L-Y—R20 groups, wherein Y represents an GLP-1/Glucagon receptor agonist moiety; and -L is a linker moiety—by formula (Ia),
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