Compounds and method for imaging cancer
US10792377B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Apr 3, 2018 |
| Grant date | Oct 6, 2020 |
| Priority date | — |
| Expiry date | Apr 3, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound, a method of imaging a cell, and a method of detecting a cancer, an inflammatory disease, or a neoplastic disease are provided. The compound includes a nitroxide derivative of a fluorophore that is activatable upon exposure to free radicals. The method of imaging a cell includes contacting the cell with an activatable nitroxide derivative of a fluorophore. The method of detecting a cancer, an inflammatory disease, or a neoplastic disease includes administering an activatable nitroxide derivative of a fluorophore and then imaging one or more cells contacted with the compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.