Method and unit for the sterile filling of a final basic container with content intended for the biopharmaceutical field

US10793299B2 · kind B2 · utility

Assignee

• Sartorius Stedim FMT SAS · FR

Inventors

• Isabelle Gay · Allauch, FR
• Nicolas Mendyk · Le Terme, FR

Key dates

• Filing date: Feb 9, 2011
• Grant date: Oct 6, 2020
• Expiry date: Oct 25, 2032

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B65B31/02
• WIPO field: Handling
• WIPO sector: Mechanical engineering

Abstract

A method for the sterile filling of at least one final basic container, includes: providing at least one sterile chamber having at least one sterile entrance port and providing a source container containing the content, located outside the chamber; providing a communication element, a dispensing element and at least one filling member, to form when all are assembled, a sterile fluid filling and transfer line; inserting at least one final container into the chamber; structurally combining at least one final container with at least one filling member; providing inner members and elements in sterile condition for a single-use; inserting the inner element and members which were previously outside the chamber in the chamber in a sterile manner, such that after filling, a new filling process can be performed without sterilizing the inside of the chamber; transferring in a filling step content from the source container into the final container.