3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives

US10793528B2 · kind B2 · utility

Assignee

• GRÜNENTHAL GMBH · DE

Inventors

• Sven Kuehnert · Lehrte, DE
• Rene Michael KOENIGS · Erkelenz, DE
• Florian Jakob · Aachen, DE
• Achim Kless · Aachen, DE
• Anita WEGERT · Aldenhoven, DE
• Paul Ratcliffe · Lanark, GB
• Ruth Jostock · Stolberg, DE
• Thomas KOCH · Stolberg, DE
• Klaus Linz · Rheinbach, DE
• Wolfgang Schroeder · Aachen, DE

Key dates

• Filing date: Jun 24, 2019
• Grant date: Oct 6, 2020
• Expiry date: Jun 24, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to 3-(carboxyethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives, their preparation and their use in medicine, particularly in the treatment of pain.