Patent · US Active

Use of chimeric antigen receptor modified cells to treat cancer

US10793638B2 · kind B2 · utility

1Cited by
6References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 30, 2018
Grant dateOct 6, 2020
Priority date
Expiry dateSep 29, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2501/515
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure relates to compositions and methods for compositions, methods, and kits for treating cancer using chimeric antigen receptor (CAR) modified cells. Some embodiments of the present disclosure relate to an isolated nucleic acid sequence encoding CAR. The CAR may include an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain. The antigen binding domain may bind to an antigen of a non-essential organ.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.