T7 RNA polymerase variants
US10793841B2 · kind B2 · utility
3Cited by
145References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 19, 2018 |
| Grant date | Oct 6, 2020 |
| Priority date | — |
| Expiry date | Sep 8, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y207/07006
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides engineered T7 RNA polymerase variants and compositions thereof. These variants have been evolved for selective incorporation of the symmetrical capped GTP analog over GTP at the initiation of in vitro transcription. The present invention also provides methods for using the variants provided herein. The present invention further provides for the use of the compositions provided herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.