Products and methods for treatment of familial amyotrophic lateral sclerosis
US10793861B2 · kind B2 · utility
8Cited by
7References
15Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jul 20, 2018 |
| Grant date | Oct 6, 2020 |
| Priority date | — |
| Expiry date | Oct 10, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2750/14143
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to RNA-based methods for inhibiting the expression of the superoxide dismutase 1 (SOD-1) gene. Recombinant adeno-associated viruses of the invention deliver DNAs encoding RNAs that knock down the expression of SOD-1. The methods have application in the treatment of amyotrophic lateral sclerosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.