Patent · US Active

Electrochemical quantitation of autoantibodies

US10794852B2 · kind B2 · utility

0Cited by

0References

5Claims

0Family size

Inventors

Robert L. Rubin · Tijeras, US
Konstantin Konstantinov · Albuquerque, US
David A. Wall · Rochester, US

Key dates

Filing date	Jan 29, 2015
Grant date	Oct 6, 2020
Priority date	—
Expiry date	Jun 26, 2035

Classification

Technology area (CPC G)Physics
CPC primaryG01N33/5438
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

This disclosure describes, in one aspect, a device for electrochemical quantitation of autoantibodies. Generally, the device includes a housing that defines a plurality of channels and at least two reaction zones. A first reaction zone includes a porous membrane and a first electrode assembly in fluid communication with a first channel. The first reaction zone also includes a first plurality of autoantigens immobilized to the porous membrane. The first electrode assembly is in communication with an amperometric reader. A second reaction zone includes a porous membrane and a second electrode assembly in fluid communication with a second channel. The second reaction zone includes a second plurality of autoantigens immobilized to the porous membrane. The second electrode assembly is in communication with the amperometric reader. Finally, the device includes a source of negative pressure in fluid communication with the first reaction zone and the second reaction zone.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.