Process for increasing the stability of a composition comprising polyunsaturated omega-3 fatty acids

US10798962B2 · kind B2 · utility

Assignee

• Evonik Operations GmbH · DE

Inventors

• Gunter Knaup · Bruchköbel, DE
• Milan Latinovic · Nidda, DE
• Michael Schwarm · Alzenau, DE

Key dates

• Filing date: Dec 17, 2015
• Grant date: Oct 13, 2020
• Expiry date: Apr 21, 2036

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2300/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A process for increasing the stability of a composition containing a polyunsaturated omega-3 fatty acid against oxidation proceeds by (i) providing a starting composition containing at least one polyunsaturated omega-3 fatty acid component; (ii) providing a lysine composition; (iii) admixing an aqueous, an aqueous-alcoholic or an alcoholic solution of starting composition and lysine composition, and subjecting resulting admixture to spray drying conditions subsequently, thus forming a solid product composition containing at least one salt of a cation derived from lysine with an anion derived from a polyunsaturated omega-3 fatty acid; the product composition exhibiting a solvent content SC selected from the following: SC<5 wt %, SC<3 wt %, SC<1 wt %, or SC<0.5 wt %.