Flexible complementary metal-oxide-semiconductor probes for chronic, large-scale neural stimulation and recording

US10799705B2 · kind B2 · utility

Assignee

• The Trustees of Columbia University in the City of New York · US

Inventors

• Kenneth L. Shepard · Johnstown, US
• David Tsai · Diamond Bar, US
• Hongki Kang · Buksang-myeon, KR
• Jordan Thimot · New York, US

Key dates

• Filing date: Feb 27, 2018
• Grant date: Oct 13, 2020
• Expiry date: Aug 20, 2038

Classification

• Technology area (CPC H): Electricity
• CPC primary: H04B5/26
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Systems and methods for providing neural stimulation and recording on a subject using flexible complementary CMOS probes are provided. Disclosed systems can include a flexible probe adapted for insertion into a portion of a brain of the subject, the flexible probe comprising a tail portion and a head portion. The tail portion can include a plurality of electrodes configured to be coupled to the brain and a plurality of front-end amplifiers. Each of the plurality of front-end amplifiers can be configured to amplify a signal received from a corresponding electrode of the plurality of electrodes. The head portion can include one or more inductors configured to enable two-way communication with a wireless reader through a near-field inductive link.