Small molecule compounds targeting PBX1 transcriptional complex
US10800742B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Apr 22, 2016 |
| Grant date | Oct 13, 2020 |
| Priority date | — |
| Expiry date | Apr 22, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/64
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In accordance with one or more embodiments, the present invention provides a compound of formulas I, II, and III, for use in methods of inhibition of PBX1-DNA interaction in a mammalian cell or population of cells, and for use in the treatment of medical conditions including but not limited to cancers, developmental disorders, inflammatory disorders, autoimmune diseases, or neuro-degenerative disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.