Rapamycin derivatives

US10800793B2 · kind B2 · utility

Assignee

• Novartis AG · CH

Inventors

• Simone BONAZZI · Cambridge, US
• Michael Connolly · Salem, US
• David Glass · Cambridge, US
• Manuel Mihalic · Wyhlen, DE
• Andrew W. Patterson · Somerville, US
• Silvio Roggo · Muttenz, CH
• Tea Shavlakadze · Cambridge, US

Key dates

• Filing date: Sep 25, 2018
• Grant date: Oct 13, 2020
• Expiry date: Sep 25, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/6561
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The disclosure relates to compounds of formula (I) and pharmaceutically acceptable salts, and compositions thereof, wherein the substituents are as defined herein. Also provided are methods of making compounds of formula (I), and methods involving the compounds or compositions for treating disorders and diseases described herein.