Patent · US Active

Chimeric cytokine receptors and encoding nucleic acids

US10800855B2 · kind B2 · utility

4Cited by

0References

15Claims

0Family size

Assignee

AUTOLUS LIMITED · GB

Inventors

Martin Pulé · London, GB
Shaun Cordoba · London, GB
Matteo Righi · London, GB
James Sillibourne · London, GB
Shimobi Onuoha · London, GB
Simon Thomas · London, GB

Key dates

Filing date	Aug 27, 2018
Grant date	Oct 13, 2020
Priority date	—
Expiry date	Aug 27, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/70
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a chimeric cytokine receptor (CCR) comprising: (i) an exodomain which binds to a ligand selected from a tumour secreted factor, a chemokine and a cell-surface antigen; and (ii) a cytokine receptor endodomain.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.