Patent · US Active

General secretory pathway (GSP) mutant listeria SPP., and methods for making and using the same

US10801030B2 · kind B2 · utility

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11Claims

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Assignee

The Regents of the University of California · US

Inventors

Daniel A. Portnoy · Albany, US
Juliana Durack · San Francisco, US
Thomas Burke · Reno, US

Key dates

Filing date	Nov 4, 2015
Grant date	Oct 13, 2020
Priority date	—
Expiry date	Dec 30, 2036

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K48/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

General secretory pathway (GSP) mutant Listeria bacteria are provided. Aspects of the bacteria include the presence of a GSP mutation, e.g., a SecY and/or SecA mutation. Also provided are methods of making and using the Listeria bacteria comprising a GSP mutation as vectors and vaccines expressing a heterologous nucleic acid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.