Online dilution for a liquid chromatography system using a sample metering pump
US10802001B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 13, 2018 |
| Grant date | Oct 13, 2020 |
| Priority date | — |
| Expiry date | Feb 6, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/347
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An apparatus for diluting a sample in a liquid chromatography system includes a metering pump, a sample needle and a sample valve. One of the sample valve ports is in fluid communication with the first pump port, a second one of the sample valve ports is in fluid communication with the second pump port, and a third one of the sample valve ports is in fluid communication with the sample needle. The sample valve can be configured in a first to conduct a solvent to the first pump port and to fluidically terminate the second pump port, and in a second state in which the sample needle is in fluid communication with the second pump port. A merge valve configurable in different states is in fluid communication with the sample valve. The states of the sample valve and merge valve can be controlled to perform online dilution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.