Formulation for use in the treatment of uremic pruritus
US10806721B2 · kind B2 · utility
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3References
15Claims
0Family size
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Key dates
| Filing date | Jun 16, 2017 |
| Grant date | Oct 20, 2020 |
| Priority date | — |
| Expiry date | Jun 16, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P17/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There is provided a topical formulation comprising a nucleophile, such as amino acids and most polypeptides and/or a derivative thereof, for use in the treatment or prevention of itchy dry skin caused by urea, such as in uremic pruritus, of a subject. The amino acid may be histidine and the derivative may be a histidine degradation product, a peptide of histidine, a peptide of histidine and one or more additional amino acids, and a pharmaceutically-acceptable salt of histidine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.