Patent · US Active

Small molecule inhibitors of XBP1 splicing

US10806725B2 · kind B2 · utility

0Cited by

1References

16Claims

0Family size

Assignee

Georgetown University · US

Inventors

Sivanesan Dakshanamurthy · Herndon, US
Milton L. Brown · Brookeville, US
Robert Clarke · Rockville, US
Ayesha N. Shajahan-Haq · Haymarket, US
Jacqueline Smith · Bowie, US

Key dates

Filing date	May 16, 2016
Grant date	Oct 20, 2020
Priority date	—
Expiry date	May 16, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Small molecule inhibitors of XBP1 splicing by IRE1α are provided, as well as methods for their use in treating or preventing cancer (e.g., endocrine resistant breast cancer), diabetes, and obesity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.