Patent · US Active

Functional cure of retroviral infection

US10806734B2 · kind B2 · utility

0Cited by

1References

9Claims

0Family size

Assignee

Katholieke Universiteit Leuven · BE

Inventors

Frauke Christ · Heverlee, BE
Zeger Debyser · Heverlee, BE
Rik Gijsbers · Blanden, BE
Lenard Vranckx · Hulshout, BE

Key dates

Filing date	May 9, 2016
Grant date	Oct 20, 2020
Priority date	—
Expiry date	May 9, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2740/16043
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The application relates to methods of curing retroviral infections, i.e. ensuring remission of retroviral infections, more particularly HIV infections, by administering a compound which is capable of binding to the LEDGF/p75 binding pocket of HIV-integrase and inhibiting LEDGF/p75-IN protein-protein interaction. The application further relates to the use of LEDGINs in retroviral gene therapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.