Oncolytic HSV1 vector and methods of use
US10806761B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | May 4, 2016 |
| Grant date | Oct 20, 2020 |
| Priority date | — |
| Expiry date | Jun 24, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/008
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Malignant tumors that are resistant to conventional therapies represent significant therapeutic challenges. An embodiment of the present invention provides a second generation oncolytic virus rQNestin34.5v2 with less toxicity that is more effective at selective killing target cells, such as tumor cells. In various embodiments presented herein, the oncolytic virus described herein is suitable for treatment of glioblastoma, as well as other cancers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.