Patent · US Active

Enhanced immunoglobulin diversity

US10813346B2 · kind B2 · utility

0Cited by

46References

12Claims

0Family size

Assignee

TRIANNI, INC. · US

Inventors

Matthias Wahl · Langquaid, DE
Bao Duong · San Francisco, US
Nigel Killeen · San Francisco, US

Key dates

Filing date	Nov 30, 2016
Grant date	Oct 27, 2020
Priority date	—
Expiry date	Nov 30, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/60
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention provides compositions and methods for enhanced production of immunoglobulin diversity. Specifically, the invention provides compositions and methods for making accessible a B cell receptor repertoire that has not been culled by developmental tolerance mechanisms. The invention also provides transgenic animals, cells, and antibodies resulting from these compositions and methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.