Antimicrobial peptoids with improved selectivity and use thereof
US10815275B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Mar 19, 2019 |
| Grant date | Oct 27, 2020 |
| Priority date | — |
| Expiry date | Mar 19, 2039 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Antimicrobial peptoids with improved selectivity to bacteria and a use thereof are described. Specifically, the antimicrobial peptoids have high antimicrobial activity and greatly decreased toxicity to animal cells. The antimicrobial peptoids show excellent antimicrobial activity against bacteria and exhibit low cytotoxicity to animal cells due to altered degree of folding in helical structure or altered charge characteristics. Therefore, the antimicrobial peptoids have improved selectivity to bacteria, and thus can be usefully used as antimicrobial compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.